Premier League Betting Preview: Manchester Derby Headlines Weekend Action With Odds and Offers Galore!

The Manchester Derby takes centre stage in this weekend’s Premier League action, with key games in the title and relegation race. We break down the odds and betting insight.
Premier League Betting Preview: Manchester Derby Headlines Weekend Action With Odds and Offers Galore!

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Jake Ashton
Jake Ashton - Your Betting Odds Guide 👍

I break betting odds news as it happens, so you’re never left behind when the market moves or a top offer lands.

  • Manchester Derby headlines a jam-packed Premier League weekend
  • Man City are favourites to win away at Old Trafford with implied odds giving them a 47.6% chance
  • Full weekend schedule includes ten fixtures, concluding with Leicester City vs. Newcastle United on Monday night

Manchester Derby Headlines Premier League Betting for April 5–7

The Premier League weekend delivers a blockbuster line-up with Manchester United hosting rivals Manchester City in the standout fixture of the matchday. 

Taking place across Saturday 5th to Monday 7th April, fans and punters alike are in for another big weekend in the Premier League.

With the title race all but wrapped up and the relegation scrap lacking a real fight, it's Derby matches that can ignite a season that looks to not have much going for it now other than the race for the European places.

City’s slight favouritism reflects recent dominance in this fixture although United ran out 2-1 winners earlier on in the season thanks to a magical display from Amad Diallo.

Bet365's latest odds for the game are:

Man Utd v Man City - 6 April 2025OddsProbability
Man Utd23/1030.3%
Draw13/527.8%
Man City11/1047.6%
What the expert says...
Ruben Amorim's men will be looking to get back to winning ways after their 1-0 loss to Nottingham Forest on Tuesday night and there's no better time to do so than against their cross-town rivals City. United are outsiders in the betting market but will be strengthened by the loss of Erling Haaland for the visitors.

Jake Ashton - Football Betting Expert - OLBG.com

Full Premier League Fixture List

  • Saturday, April 5

    • 12:30 BST: Everton vs. Arsenal – Goodison Park, Liverpool

    • 15:00 BST: Crystal Palace vs. Brighton & Hove Albion – Selhurst Park, London

    • 15:00 BST: Ipswich Town vs. Wolverhampton Wanderers – Portman Road, Ipswich

    • 15:00 BST: West Ham United vs. AFC Bournemouth – London Stadium, London

    • 17:30 BST: Aston Villa vs. Nottingham Forest – Villa Park, Birmingham

  • Sunday, April 6

    • 14:00 BST: Brentford vs. Chelsea – Gtech Community Stadium, Brentford

    • 14:00 BST: Fulham vs. Liverpool – Craven Cottage, London

    • 14:00 BST: Tottenham Hotspur vs. Southampton – Tottenham Hotspur Stadium, London

    • 16:30 BST: Manchester United vs. Manchester City – Old Trafford, Manchester

  • Monday, April 7

    • 20:00 BST: Leicester City vs. Newcastle United – King Power Stadium, Leicester

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